{"id":9372,"date":"2026-10-31T03:16:47","date_gmt":"2026-10-31T00:16:47","guid":{"rendered":"https:\/\/merkezlaboratuvari.com\/?p=9372"},"modified":"2026-10-31T03:16:47","modified_gmt":"2026-10-31T00:16:47","slug":"anti-hbc-nedir","status":"publish","type":"post","link":"https:\/\/merkezlaboratuvari.com\/ar\/anti-hbc-nedir\/","title":{"rendered":"Anti-HBc Nedir? IgG, Total ve Pozitif Sonu\u00e7"},"content":{"rendered":"<p>Anti-HBc nedir sorusunun k\u0131sa yan\u0131t\u0131: anti-HBc, hepatit B vir\u00fcs\u00fcn\u00fcn kor (\u00e7ekirdek) antijenine kar\u015f\u0131 olu\u015fan antikordur ve ki\u015finin vir\u00fcsle daha \u00f6nce kar\u015f\u0131la\u015f\u0131p kar\u015f\u0131la\u015fmad\u0131\u011f\u0131n\u0131 g\u00f6sterir. Pozitif sonu\u00e7 hem iyile\u015fmi\u015f hem de s\u00fcregen enfeksiyonda g\u00f6r\u00fclebilir; bu nedenle tek ba\u015f\u0131na &#8220;hastal\u0131k var&#8221; ya da &#8220;ba\u011f\u0131\u015f\u0131kl\u0131k var&#8221; anlam\u0131na gelmez ve HBsAg ile anti-HBs sonu\u00e7lar\u0131yla birlikte okunur.<\/p>\n<p>Bu sayfada total, IgG ve IgM anti-HBc aras\u0131ndaki fark, pozitif ve negatif sonucun genel anlam\u0131, yaln\u0131zca anti-HBc&#8217;nin pozitif oldu\u011fu durumun olas\u0131 nedenleri ve ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 bask\u0131layan tedavi \u00f6ncesinde bu testin neden \u00f6nem ta\u015f\u0131d\u0131\u011f\u0131 anlat\u0131l\u0131r. Bilgiler genel bilgilendirme ama\u00e7l\u0131d\u0131r; ki\u015fisel de\u011ferlendirme i\u00e7in hekime ba\u015fvurulmal\u0131d\u0131r.<\/p>\n<blockquote>\n<p><strong>\u00d6zet<\/strong><br \/>\n&#8211; Anti-HBc, vir\u00fcs\u00fcn kor antijenine kar\u015f\u0131 olu\u015fan antikordur; vir\u00fcsle kar\u015f\u0131la\u015f\u0131lan her durumda geli\u015fir ve genellikle \u00f6m\u00fcr boyu pozitif kal\u0131r.<br \/>\n&#8211; Hepatit B a\u015f\u0131s\u0131 anti-HBc olu\u015fturmaz; a\u015f\u0131yla ba\u011f\u0131\u015f\u0131k ki\u015fide anti-HBc negatiftir.<br \/>\n&#8211; Anti-HBc pozitifli\u011fi tek ba\u015f\u0131na aktif enfeksiyon anlam\u0131na gelmez; HBsAg ve anti-HBs ile birlikte yorumlan\u0131r.<br \/>\n&#8211; Yaln\u0131zca anti-HBc pozitifli\u011fi (izole anti-HBc) birden fazla nedene ba\u011fl\u0131 olabilir.<br \/>\n&#8211; Yorum ve karar hekime aittir.<\/p>\n<\/blockquote>\n<h2>Anti-HBc Nedir?<\/h2>\n<p>Hepatit B vir\u00fcs\u00fcn\u00fcn (HBV) i\u00e7inde, genetik materyali saran kor (\u00e7ekirdek) proteini bulunur. Ba\u011f\u0131\u015f\u0131kl\u0131k sistemi bu proteine kar\u015f\u0131 anti-HBc antikorunu \u00fcretir. CDC&#8217;ye g\u00f6re total anti-HBc, \u00e7\u00f6z\u00fclm\u00fc\u015f de olsa s\u00fcren de olsa t\u00fcm HBV enfeksiyonlar\u0131nda geli\u015fir ve genellikle \u00f6m\u00fcr boyu kal\u0131r; hepatit B a\u015f\u0131s\u0131yla ba\u011f\u0131\u015f\u0131kl\u0131k kazanan ki\u015filerde ise geli\u015fmez (CDC 2023).<\/p>\n<p>Bu \u00f6zellik, anti-HBc&#8217;yi anti-HBs&#8217;den ay\u0131r\u0131r. <a href=\"\/test-listesi\/anti-hbs\/\">Anti-HBs<\/a> hem a\u015f\u0131yla hem iyile\u015fmi\u015f enfeksiyonla pozitif olabilirken, anti-HBc yaln\u0131zca vir\u00fcsle kar\u015f\u0131la\u015fm\u0131\u015f ki\u015filerde pozitiftir. \u00dc\u00e7 testin birlikte okunu\u015fu i\u00e7in hepatit B tahlilleri yaz\u0131s\u0131na bak\u0131labilir. Bkz. <a href=\"\/hepatit-b-tahlilleri\/\">Hepatit B Tahlilleri<\/a>.<\/p>\n<h2>Total, IgG ve IgM Anti-HBc Aras\u0131ndaki Fark<\/h2>\n<p>Laboratuvar raporlar\u0131nda anti-HBc farkl\u0131 adlarla g\u00f6r\u00fclebilir:<\/p>\n\n<figure class=\"wp-block-table\"><table>\n<thead>\n<tr>\n<th>Rapordaki ad<\/th>\n<th>Neyi \u00f6l\u00e7er<\/th>\n<th>Genel kullan\u0131m<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><a href=\"\/test-listesi\/anti-hbc-total\/\">Anti-HBc total<\/a><\/td>\n<td>IgG ve IgM s\u0131n\u0131f\u0131 antikorlar\u0131n toplam\u0131<\/td>\n<td>Vir\u00fcsle kar\u015f\u0131la\u015f\u0131l\u0131p kar\u015f\u0131la\u015f\u0131lmad\u0131\u011f\u0131n\u0131 g\u00f6steren temel test; CDC 2023&#8217;\u00fcn \u00f6nerdi\u011fi \u00fc\u00e7 testlik tarama panelinde yer al\u0131r<\/td>\n<\/tr>\n<tr>\n<td>Anti-HBc IgG<\/td>\n<td>Bir\u00e7ok raporda total testin bu adla yaz\u0131ld\u0131\u011f\u0131 g\u00f6r\u00fcl\u00fcr; CDC&#8217;ye g\u00f6re yaln\u0131zca IgG&#8217;yi \u00f6l\u00e7en ayr\u0131 bir test ticari olarak bulunmaz<\/td>\n<td>TKAD k\u0131lavuzu ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 bask\u0131layan tedavi \u00f6ncesi taramada bu ad\u0131 kullan\u0131r; hangi testin kastedildi\u011fi laboratuvardan \u00f6\u011frenilir<\/td>\n<\/tr>\n<tr>\n<td><a href=\"\/test-listesi\/anti-hbc-igm\/\">Anti-HBc IgM<\/a><\/td>\n<td>Yaln\u0131zca IgM s\u0131n\u0131f\u0131 antikor<\/td>\n<td>Yak\u0131n zamanl\u0131 (akut) enfeksiyonda y\u00fckselir; CDC&#8217;ye g\u00f6re yaln\u0131zca akut enfeksiyondan \u015f\u00fcphelenildi\u011finde istenmelidir<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/figure>\n\n<p>Kronik enfeksiyonda IgM anti-HBc genellikle negatiftir, ancak \u015fiddetli alevlenme ya da reaktivasyon d\u00f6nemlerinde pozitifle\u015febilir (CDC 2023). Bu nedenle IgM sonucu tek ba\u015f\u0131na akut ya da kronik ayr\u0131m\u0131 i\u00e7in yeterli say\u0131lmaz.<\/p>\n<h2>Anti-HBc Pozitif Ne Demek?<\/h2>\n<p>Anti-HBc nedir sorusunun pozitif sonu\u00e7la ilgili yan\u0131t\u0131 \u015fudur: anti-HBc pozitifli\u011fi hepatit B vir\u00fcs\u00fcyle kar\u015f\u0131la\u015f\u0131ld\u0131\u011f\u0131n\u0131 g\u00f6sterir. Bunun hangi anlama geldi\u011fi HBsAg ve anti-HBs sonu\u00e7lar\u0131na ba\u011fl\u0131d\u0131r:<\/p>\n<ul>\n<li><strong>HBsAg pozitif:<\/strong> Vir\u00fcs kanda bulunmaktad\u0131r; akut ya da kronik enfeksiyon d\u00fc\u015f\u00fcn\u00fcl\u00fcr. Ayr\u0131m IgM anti-HBc, HBV DNA ve klinik de\u011ferlendirmeyle yap\u0131l\u0131r. Ayr\u0131nt\u0131 i\u00e7in <a href=\"\/hbsag-nedir\/\">HBsAg nedir<\/a> yaz\u0131s\u0131na bak\u0131labilir.<\/li>\n<li><strong>HBsAg negatif, anti-HBs pozitif:<\/strong> \u0130yile\u015fmi\u015f enfeksiyon d\u00fc\u015f\u00fcn\u00fcl\u00fcr. Ba\u011f\u0131\u015f\u0131kl\u0131k s\u00f6z konusudur; anti-HBc genellikle \u00f6m\u00fcr boyu pozitif kal\u0131r.<\/li>\n<li><strong>HBsAg negatif, anti-HBs negatif:<\/strong> \u0130zole anti-HBc ad\u0131 verilen durumdur (a\u015fa\u011f\u0131da).<\/li>\n<\/ul>\n<p>Anti-HBc pozitifli\u011fi, iyile\u015fmi\u015f enfeksiyonda da g\u00f6r\u00fcld\u00fc\u011f\u00fc i\u00e7in tek ba\u015f\u0131na &#8220;hastal\u0131k&#8221; anlam\u0131na gelmez.<\/p>\n<h2>Anti-HBc Negatif Ne Demek?<\/h2>\n<p>Anti-HBc negatifli\u011fi genel olarak vir\u00fcsle kar\u015f\u0131la\u015f\u0131lmad\u0131\u011f\u0131n\u0131 d\u00fc\u015f\u00fcnd\u00fcr\u00fcr. Hepatit B a\u015f\u0131s\u0131yla ba\u011f\u0131\u015f\u0131kl\u0131k kazanm\u0131\u015f ki\u015fide de anti-HBc negatif bulunur; \u00e7\u00fcnk\u00fc a\u015f\u0131 kor antijenine kar\u015f\u0131 antikor olu\u015fturmaz. Anti-HBc negatif ve anti-HBs pozitif bir profil bu nedenle a\u015f\u0131ya ba\u011fl\u0131 ba\u011f\u0131\u015f\u0131kl\u0131kla uyumludur. \u00c7ok yak\u0131n zamanl\u0131 bir temas s\u00f6z konusuysa antikorlar hen\u00fcz olu\u015fmam\u0131\u015f olabilir; test zamanlamas\u0131 hekim taraf\u0131ndan belirlenir.<\/p>\n<h2>\u0130zole Anti-HBc: Yaln\u0131zca Anti-HBc Pozitifse<\/h2>\n<p>HBsAg ve anti-HBs negatif, anti-HBc pozitif oldu\u011funda tek bir yorum yoktur. CDC bu profil i\u00e7in \u015fu olas\u0131l\u0131klar\u0131 sayar:<\/p>\n<ul>\n<li>Ge\u00e7irilmi\u015f enfeksiyondan sonra anti-HBs d\u00fczeyinin \u00f6l\u00e7\u00fclemeyecek kadar azalmas\u0131,<\/li>\n<li>Gizli (ok\u00fclt) hepatit B enfeksiyonu: HBsAg negatif olmas\u0131na ra\u011fmen vir\u00fcs\u00fcn bulunmas\u0131; HBV DNA genellikle saptanamaz ya da \u00e7ok d\u00fc\u015f\u00fckt\u00fcr (TKAD 2023),<\/li>\n<li>Akut enfeksiyonda anti-HBs olu\u015fmadan \u00f6nceki k\u0131sa d\u00f6nem,<\/li>\n<li>Yanl\u0131\u015f pozitif sonu\u00e7; \u00f6zellikle bilinen bir risk \u00f6yk\u00fcs\u00fc yoksa, CDC tekrar test yap\u0131lmas\u0131ndan s\u00f6z eder,<\/li>\n<li>HBsAg&#8217;nin standart testlerde saptanamayan bir varyant\u0131,<\/li>\n<li>Bebeklerde anneden pasif ge\u00e7en antikor; CDC bu nedenle 24 aydan k\u00fc\u00e7\u00fck \u00e7ocuklarda anti-HBc testini endike g\u00f6rmez.<\/li>\n<\/ul>\n<p>Nedeni ay\u0131rt etmek i\u00e7in hekim HBV DNA gibi ek testler isteyebilir. Sonucun hangi gruba girdi\u011fi yaln\u0131zca ki\u015fisel \u00f6yk\u00fc, a\u015f\u0131 durumu ve di\u011fer testlerle belirlenebilir.<\/p>\n<h2>Ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 Bask\u0131layan Tedavi \u00d6ncesinde Anti-HBc&#8217;nin Yeri<\/h2>\n<p>TKAD 2023 k\u0131lavuzuna g\u00f6re ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 bask\u0131layan tedavi (kemoterapi, biyolojik ila\u00e7lar, organ nakli gibi) alacak ki\u015filerde HBsAg, anti-HBc IgG ve anti-HBs taramas\u0131 yap\u0131lmal\u0131d\u0131r; HBsAg ve\/veya anti-HBc IgG pozitifse HBV DNA bak\u0131lmas\u0131 gerekir. Gerek\u00e7e, ge\u00e7irilmi\u015f ya da gizli enfeksiyonun bu tedaviler s\u0131ras\u0131nda yeniden etkinle\u015febilmesidir. K\u0131lavuz, bu ki\u015filerde koruyucu (profilaktik) tedavi ya da izlem yakla\u015f\u0131mlar\u0131ndan birine hekimin karar verece\u011fini belirtir. Bu bilgi genel bir \u00e7er\u00e7evedir; ki\u015fiye \u00f6zg\u00fc plan hekime aittir.<\/p>\n<h2>Numune ve Sonu\u00e7 S\u00fcresi<\/h2>\n<p>Testin numune t\u00fcr\u00fc, haz\u0131rl\u0131k gereksinimi, y\u00f6ntemi ve raporlama zaman\u0131 <a href=\"\/test-listesi\/anti-hbc-total\/\">anti-HBc total test sayfas\u0131nda<\/a> belirtilir. A\u015f\u0131 \u00f6yk\u00fcs\u00fc ve ge\u00e7irilmi\u015f sar\u0131l\u0131k gibi bilgiler hekimle ve laboratuvarla payla\u015f\u0131lmal\u0131d\u0131r.<\/p>\n<h2>Ne Zaman Hekime Ba\u015fvurulmal\u0131?<\/h2>\n<p>Anti-HBc nedir sorusunun yan\u0131t\u0131 genel bilgidir; pozitif bulundu\u011funda, \u00f6zellikle HBsAg ve anti-HBs sonu\u00e7lar\u0131yla birlikte de\u011ferlendirilmesi gerekir. Yaln\u0131zca anti-HBc pozitifse, gebelik varsa, ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 bask\u0131layan bir tedavi planlan\u0131yorsa, karaci\u011fer testlerinde a\u00e7\u0131klanamayan bir y\u00fckseklik varsa ya da sar\u0131l\u0131k, s\u00fcrekli halsizlik ve koyu renkli idrar gibi \u015fik\u00e2yetler ortaya \u00e7\u0131km\u0131\u015fsa de\u011ferlendirme hekim taraf\u0131ndan yap\u0131lmal\u0131d\u0131r. Sonu\u00e7 tek ba\u015f\u0131na yorumlan\u0131p a\u015f\u0131 ya da ba\u015fka bir karar i\u00e7in dayanak yap\u0131lmamal\u0131d\u0131r.<\/p>\n<h2>S\u0131k\u00e7a Sorulan Sorular<\/h2>\n<h3>Anti-HBc nedir?<\/h3>\n<p>Anti-HBc, hepatit B vir\u00fcs\u00fcn\u00fcn kor (\u00e7ekirdek) antijenine kar\u015f\u0131 olu\u015fan antikordur. Vir\u00fcsle kar\u015f\u0131la\u015f\u0131lan her durumda, enfeksiyon iyile\u015fmi\u015f de olsa s\u00fcregen de olsa geli\u015fir ve genellikle \u00f6m\u00fcr boyu pozitif kal\u0131r. Hepatit B a\u015f\u0131s\u0131yla olu\u015fmaz. Sonu\u00e7 HBsAg ve anti-HBs ile birlikte hekim taraf\u0131ndan yorumlan\u0131r.<\/p>\n<h3>Anti-HBc IgG ile total anti-HBc aras\u0131ndaki fark nedir?<\/h3>\n<p>Total anti-HBc, IgG ve IgM s\u0131n\u0131f\u0131 anti-HBc antikorlar\u0131n\u0131n toplam\u0131n\u0131 \u00f6l\u00e7er ve vir\u00fcsle kar\u015f\u0131la\u015f\u0131l\u0131p kar\u015f\u0131la\u015f\u0131lmad\u0131\u011f\u0131n\u0131 g\u00f6sterir. Raporlarda IgG ad\u0131yla yaz\u0131lan test de \u00e7o\u011fu zaman total testtir; hangisinin kastedildi\u011fi laboratuvardan \u00f6\u011frenilir. IgM anti-HBc ise yak\u0131n zamanl\u0131 (akut) enfeksiyon \u015f\u00fcphesinde istenen ayr\u0131 bir testtir.<\/p>\n<h3>Anti-HBc pozitif ne demek?<\/h3>\n<p>Anti-HBc pozitifli\u011fi hepatit B vir\u00fcs\u00fcyle kar\u015f\u0131la\u015f\u0131ld\u0131\u011f\u0131n\u0131 g\u00f6sterir. HBsAg pozitifse aktif enfeksiyon, HBsAg negatif ve anti-HBs pozitifse iyile\u015fmi\u015f enfeksiyon d\u00fc\u015f\u00fcn\u00fcl\u00fcr. Yaln\u0131zca anti-HBc pozitifse nedeni ek de\u011ferlendirmeyle belirlenir. Yorum hekime aittir.<\/p>\n<h3>Anti-HBc negatif ne demek?<\/h3>\n<p>Anti-HBc negatifli\u011fi genel olarak hepatit B vir\u00fcs\u00fcyle kar\u015f\u0131la\u015f\u0131lmad\u0131\u011f\u0131n\u0131 d\u00fc\u015f\u00fcnd\u00fcr\u00fcr. A\u015f\u0131yla ba\u011f\u0131\u015f\u0131kl\u0131k kazanm\u0131\u015f ki\u015fide de anti-HBc negatif bulunur. \u00c7ok yak\u0131n zamanl\u0131 bir temas s\u00f6z konusuysa test zamanlamas\u0131 hekim taraf\u0131ndan de\u011ferlendirilir.<\/p>\n<h3>Yaln\u0131zca anti-HBc pozitif \u00e7\u0131karsa ne anlama gelir?<\/h3>\n<p>HBsAg ve anti-HBs negatifken anti-HBc&#8217;nin pozitif olmas\u0131 izole anti-HBc olarak adland\u0131r\u0131l\u0131r. CDC; ge\u00e7irilmi\u015f enfeksiyondan sonra anti-HBs&#8217;nin azalmas\u0131n\u0131, gizli enfeksiyonu, anti-HBs olu\u015fmadan \u00f6nceki k\u0131sa d\u00f6nemi, yanl\u0131\u015f pozitifli\u011fi ve testte saptanamayan vir\u00fcs varyantlar\u0131n\u0131 olas\u0131 nedenler olarak sayar. Nedeni hekim belirler.<\/p>\n<h3>Anti-HBc pozitifse hastal\u0131k var demek midir?<\/h3>\n<p>Hay\u0131r, tek ba\u015f\u0131na hastal\u0131k anlam\u0131na gelmez. Anti-HBc, iyile\u015fmi\u015f enfeksiyonda da pozitiftir. Aktif enfeksiyon HBsAg ve gerekirse HBV DNA gibi testlerle de\u011ferlendirilir.<\/p>\n<h3>Ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 bask\u0131layan tedaviden \u00f6nce anti-HBc neden bak\u0131l\u0131r?<\/h3>\n<p>TKAD k\u0131lavuzuna g\u00f6re ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 bask\u0131layan tedavi alacak ki\u015filerde HBsAg, anti-HBc IgG ve anti-HBs taramas\u0131 yap\u0131l\u0131r; HBsAg ve\/veya anti-HBc pozitifse HBV DNA bak\u0131l\u0131r, \u00e7\u00fcnk\u00fc ge\u00e7irilmi\u015f enfeksiyon bu tedaviler s\u0131ras\u0131nda yeniden etkinle\u015febilir. De\u011ferlendirme hekime aittir.<\/p>\n<h2>\u0130lgili Testler ve Yaz\u0131lar<\/h2>\n<ul>\n<li><a href=\"\/test-listesi\/anti-hbc-total\/\">Anti-HBc total test sayfas\u0131<\/a><\/li>\n<li><a href=\"\/test-listesi\/anti-hbc-igm\/\">Anti-HBc IgM test sayfas\u0131<\/a><\/li>\n<li><a href=\"\/hbsag-nedir\/\">HBsAg nedir? Pozitif ve negatif ne anlama gelir<\/a><\/li>\n<li><a href=\"\/hepatit-b-tahlilleri\/\">Hepatit B Tahlilleri<\/a><\/li>\n<li><a href=\"\/anti-hbs-nedir\/\">Anti-HBs Nedir?<\/a><\/li>\n<li><a href=\"\/hbv-dna-nedir\/\">HBV DNA Nedir?<\/a><\/li>\n<\/ul>\n<blockquote>\n<p><strong>Merkez T\u0131bbi Tahlil Laboratuvar\u0131<\/strong><br \/>\nKayaba\u015f\u0131, Kaya\u015fehir Blv. Sitesi No:40, 34220 Ba\u015fak\u015fehir\/\u0130stanbul<br \/>\nTelefon: 0212 610 01 30 (WhatsApp hatt\u0131 mevcuttur)<br \/>\n\u00c7al\u0131\u015fma saatleri: Pazartesi\u2013Cumartesi 08:30\u201318:00, Pazar kapal\u0131<br \/>\nRandevu uygulamas\u0131 bulunmamaktad\u0131r; hasta kabul\u00fc \u00e7al\u0131\u015fma saatleri i\u00e7inde yap\u0131lmaktad\u0131r.<br \/>\nArap\u00e7a bilgilendirme hizmeti mevcuttur. Sonu\u00e7lar online olarak sorgulanabilmektedir.<br \/>\n\u0130leti\u015fim: <a href=\"\/iletisim\/\">ileti\u015fim sayfas\u0131<\/a><\/p>\n<p><strong>Uyar\u0131:<\/strong> Bu sayfa yaln\u0131zca genel bilgilendirme ama\u00e7l\u0131d\u0131r; tan\u0131, tedavi veya t\u0131bbi karar yerine ge\u00e7mez. Test sonu\u00e7lar\u0131 hekim taraf\u0131ndan de\u011ferlendirilmelidir.<\/p>\n<\/blockquote>\n<p><strong>Kaynaklar<\/strong>:<br \/>\n&#8211; <a href=\"https:\/\/www.cdc.gov\/mmwr\/volumes\/72\/rr\/rr7201a1.htm\" rel=\"nofollow noopener\" target=\"_blank\">Conners EE ve ark., Screening and Testing for Hepatitis B Virus Infection: CDC Recommendations, United States, 2023, MMWR Recomm Rep 2023;72(RR-1)<\/a><br \/>\n&#8211; <a href=\"https:\/\/www.tkad.org.tr\/wp-content\/uploads\/2023\/11\/TURKIYE-HEPATIT-B-TANI-VE-TEDAVI-KLAVUZU-2023.pdf\" rel=\"nofollow noopener\" target=\"_blank\">T\u00fcrk Karaci\u011fer Ara\u015ft\u0131rmalar\u0131 Derne\u011fi (TKAD), T\u00fcrkiye Hepatit B Tan\u0131 ve Tedavi K\u0131lavuzu, 2023<\/a><\/p>\n<p><strong>Son g\u00fcncelleme<\/strong>: 30 Ekim 2026<\/p>\n\n<script type=\"application\/ld+json\">\n{\n \"@context\": \"https:\/\/schema.org\",\n \"@graph\": [\n {\n \"@type\": \"MedicalWebPage\",\n \"name\": \"Anti-HBc Nedir? IgG, Total ve Pozitif Sonu\u00e7\",\n \"url\": \"https:\/\/merkezlaboratuvari.com\/anti-hbc-nedir\/\",\n \"inLanguage\": \"tr\",\n \"about\": { \"@type\": \"MedicalTest\", \"name\": \"Anti-HBc (hepatit B kor antikoru)\" },\n \"dateModified\": \"2026-10-30\",\n \"publisher\": { \"@type\": \"Organization\", \"name\": \"Merkez T\u0131bbi Tahlil Laboratuvar\u0131\" }\n },\n {\n \"@type\": \"FAQPage\",\n \"mainEntity\": [\n {\"@type\": \"Question\", \"name\": \"Anti-HBc nedir?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Anti-HBc, hepatit B vir\u00fcs\u00fcn\u00fcn kor (\u00e7ekirdek) antijenine kar\u015f\u0131 olu\u015fan antikordur. Vir\u00fcsle kar\u015f\u0131la\u015f\u0131lan her durumda, enfeksiyon iyile\u015fmi\u015f de olsa s\u00fcregen de olsa geli\u015fir ve genellikle \u00f6m\u00fcr boyu pozitif kal\u0131r. Hepatit B a\u015f\u0131s\u0131yla olu\u015fmaz. Sonu\u00e7 HBsAg ve anti-HBs ile birlikte hekim taraf\u0131ndan yorumlan\u0131r.\"}},\n {\"@type\": \"Question\", \"name\": \"Anti-HBc IgG ile total anti-HBc aras\u0131ndaki fark nedir?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Total anti-HBc, IgG ve IgM s\u0131n\u0131f\u0131 anti-HBc antikorlar\u0131n\u0131n toplam\u0131n\u0131 \u00f6l\u00e7er ve vir\u00fcsle kar\u015f\u0131la\u015f\u0131l\u0131p kar\u015f\u0131la\u015f\u0131lmad\u0131\u011f\u0131n\u0131 g\u00f6sterir. Raporlarda IgG ad\u0131yla yaz\u0131lan test de \u00e7o\u011fu zaman total testtir; hangisinin kastedildi\u011fi laboratuvardan \u00f6\u011frenilir. IgM anti-HBc ise yak\u0131n zamanl\u0131 (akut) enfeksiyon \u015f\u00fcphesinde istenen ayr\u0131 bir testtir.\"}},\n {\"@type\": \"Question\", \"name\": \"Anti-HBc pozitif ne demek?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Anti-HBc pozitifli\u011fi hepatit B vir\u00fcs\u00fcyle kar\u015f\u0131la\u015f\u0131ld\u0131\u011f\u0131n\u0131 g\u00f6sterir. HBsAg pozitifse aktif enfeksiyon, HBsAg negatif ve anti-HBs pozitifse iyile\u015fmi\u015f enfeksiyon d\u00fc\u015f\u00fcn\u00fcl\u00fcr. Yaln\u0131zca anti-HBc pozitifse nedeni ek de\u011ferlendirmeyle belirlenir. Yorum hekime aittir.\"}},\n {\"@type\": \"Question\", \"name\": \"Anti-HBc negatif ne demek?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Anti-HBc negatifli\u011fi genel olarak hepatit B vir\u00fcs\u00fcyle kar\u015f\u0131la\u015f\u0131lmad\u0131\u011f\u0131n\u0131 d\u00fc\u015f\u00fcnd\u00fcr\u00fcr. 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Nedeni hekim belirler.\"}},\n {\"@type\": \"Question\", \"name\": \"Anti-HBc pozitifse hastal\u0131k var demek midir?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Hay\u0131r, tek ba\u015f\u0131na hastal\u0131k anlam\u0131na gelmez. Anti-HBc, iyile\u015fmi\u015f enfeksiyonda da pozitiftir. Aktif enfeksiyon HBsAg ve gerekirse HBV DNA gibi testlerle de\u011ferlendirilir.\"}},\n {\"@type\": \"Question\", \"name\": \"Ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 bask\u0131layan tedaviden \u00f6nce anti-HBc neden bak\u0131l\u0131r?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"TKAD k\u0131lavuzuna g\u00f6re ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 bask\u0131layan tedavi alacak ki\u015filerde HBsAg, anti-HBc IgG ve anti-HBs taramas\u0131 yap\u0131l\u0131r; HBsAg ve\/veya anti-HBc pozitifse HBV DNA bak\u0131l\u0131r, \u00e7\u00fcnk\u00fc ge\u00e7irilmi\u015f enfeksiyon bu tedaviler s\u0131ras\u0131nda yeniden etkinle\u015febilir. 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Pozitif sonu\u00e7 hem iyile\u015fmi\u015f hem de s\u00fcregen enfeksiyonda g\u00f6r\u00fclebilir; bu nedenle tek ba\u015f\u0131na &#8220;hastal\u0131k var&#8221; ya da &#8220;ba\u011f\u0131\u015f\u0131kl\u0131k var&#8221; anlam\u0131na gelmez ve HBsAg ile anti-HBs sonu\u00e7lar\u0131yla birlikte okunur. Bu sayfada total, IgG [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-9372","post","type-post","status-publish","format-standard","hentry","category-saglik"],"_links":{"self":[{"href":"https:\/\/merkezlaboratuvari.com\/ar\/wp-json\/wp\/v2\/posts\/9372","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/merkezlaboratuvari.com\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/merkezlaboratuvari.com\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/merkezlaboratuvari.com\/ar\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/merkezlaboratuvari.com\/ar\/wp-json\/wp\/v2\/comments?post=9372"}],"version-history":[{"count":4,"href":"https:\/\/merkezlaboratuvari.com\/ar\/wp-json\/wp\/v2\/posts\/9372\/revisions"}],"predecessor-version":[{"id":9463,"href":"https:\/\/merkezlaboratuvari.com\/ar\/wp-json\/wp\/v2\/posts\/9372\/revisions\/9463"}],"wp:attachment":[{"href":"https:\/\/merkezlaboratuvari.com\/ar\/wp-json\/wp\/v2\/media?parent=9372"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/merkezlaboratuvari.com\/ar\/wp-json\/wp\/v2\/categories?post=9372"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/merkezlaboratuvari.com\/ar\/wp-json\/wp\/v2\/tags?post=9372"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}